MMRV programme: information for healthcare practitioners

Source: UK Health Security Agency Date: 2026-02-10 Category: Guidance Feed: ukhsa_official

Summary

The UK has launched a combined MMRV (measles, mumps, rubella and varicella) vaccination programme effective 1 January 2026 in England. This adds chickenpox protection to existing MMR coverage, representing a significant expansion of the routine childhood immunisation schedule.

Vaccination Schedule

Children receive the MMRV vaccine at two key timepoints:

  • 12 months of age (first dose)
  • 18 months of age (second dose)

Core Purpose

The programme “adds protection against chickenpox to the existing provision of protection against measles, mumps, and rubella,” addressing a vaccine-preventable disease that previously was not part of the routine UK immunisation schedule.

Key Resources for Healthcare Practitioners

  1. Main guidance document — covers eligibility criteria, administration protocols, and safety information
  2. Appendix A — eligibility tables in printable format for clinical reference
  3. Training slideset — available for professional development and team education

Recent Updates (February 2026)

The guidance has been refined to address:

  • Ibuprofen use during vaccination
  • Managing immunisation for children with ongoing close contact to pregnant women
  • Catch-up cohort eligibility clarifications
  • IT system compatibility issues
  • Vaccination protocols for children with current infections

Implementation Notes

  • This guidance specifically applies to England
  • Targets healthcare professionals administering the new routine immunisation programme
  • Regular updates reflect real-world implementation challenges and clinical questions

Public Health Significance

The addition of varicella to the routine immunisation schedule represents a major policy shift, potentially reducing chickenpox burden in children and complications in vulnerable populations. Integration into the existing MMR schedule as MMRV aims to maintain high coverage while expanding protection.


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