摘要
On 11 March 2025, the World Health Organization (WHO) received a report from the International Health Regulation (2005) (IHR) National Focal Point (NFP) of the United States of America (United States) on the ongoing measles outbreak in the country, notified under IHR because it is an unusual event with potential significant public health impact, with the number of cases and deaths in 2025 exceeding the numbers in previous years. Additionally, cases linked to the outbreak in the State of Texas, United States, have been reported in Mexico. Measles is a highly contagious, airborne viral disease that can lead to severe complications and death. From 1 January to 20 March 2025, 17 States have reported a total of 378 cases of measles, including two deaths - the first deaths related to measles in the United States in a decade. The majority of cases are in children who are unvaccinated or have unknown vaccination status, and the overall hospitalization rate is 17%. In 2025, within the larger public health event, there are three distinct measles outbreaks reported, accounting for 90% (341/378) of reported cases. The Centers for Disease Control and Prevention of the United States (US CDC) and other government agencies are working to control the outbreaks. In 2000, measles was declared eliminated in the United States, since then imported cases of measles have been detected in the country, as the disease remains endemic in many parts of the world.
WHO is working closely with countries in the WHO Region of the Americas to prevent the spread and reintroduction of measles.
詳細內容
On 11 March 2025, the NFP of the United States notified to WHO an ongoing outbreak of measles in the United States.From 1 January to 20 March 2025, 378 cases have been reported from 17 States including: Alaska, California, Florida, Georgia, Kansas, Kentucky, Maryland, Michigan, New Jersey, New Mexico, New York State, Ohio, Pennsylvania, Rhode Island, Texas, Vermont, and Washington. Two deaths have also been reported, one confirmed in Texas and one under investigation in New Mexico. The majority of cases are in children who are unvaccinated or have unknown vaccination status. The hospitalization rate is 17%. Ninety percent of the 378 cases (341 cases) have been associated with three distinct outbreaks (defined as three or more related cases) reported in 2025, while the remainder are sporadic cases that are part of the larger outbreak.From late January until 14 March 2025, the Texas Department of State Health Services reported 259 cases in the South Plains and Panhandle regions of Texas. Of these, 34 patients have been hospitalized, and 257 (99%) were unvaccinated or with unknown vaccination status. In February 2025, an unvaccinated school-aged child who lived in the Texas outbreak area died of measles. This was the first death in the United States related to measles in a decade. As of 14 March, the New Mexico Department of Health reported 35 cases of measles. Of the 35 cases, 28 were unvaccinated, two were vaccinated, and five had unknown vaccination status.From 1 January 2025 to 20 March 2025, the US CDC reported 128 measles DNA sequences. Texas submitted 92 identical DNA sequences in genotype D8; while 10 DNA sequences from New Mexico and one DNA sequence from Kansas were identical to those from Texas. Texas also reported three genotype D8 sequences (a total of 19 D8 sequences have been reported from the affected States) with single nucleotide substitutions. Additionally, a total of five distinct genotype B3 sequences were reported from the States of Alaska, California, Florida, Kentucky, New York, Rhode Island, Texas, and Washington. The source of this outbreak is unknown. Currently, there is no evidence of decreased vaccine effectiveness or changes in the virus that would result in increased severity.In 2000, measles was declared eliminated[1] in the United States and, since then, imported cases of measles have been detected in the country since the disease remains endemic in many parts of the world. The United States last verified the ongoing elimination of measles in 2024. In 2023, the vaccination coverage rate for two doses of measles, mumps, and rubella (MMR) vaccine among children in kindergarten in the United States was 92.7%.
影響地區
- On
- United States
- States
- Alaska
- California
- Florida
- Georgia
- Kansas
- Kentucky
- Maryland
相關疾病
萃取時間: 2026-02-05T15:09:20Z 資料來源: WHO Disease Outbreak News