Research: Pertussis: laboratory confirmed cases reported in England 2025

摘要

Enhanced surveillance data on laboratory confirmed pertussis (whooping cough) cases reported in England during 2025, tracking disease burden and trends.

詳細內容

This research publication presents laboratory confirmed cases of pertussis reported to the enhanced pertussis surveillance programme in England for 2025. Pertussis (whooping cough) is a highly contagious respiratory disease caused by Bordetella pertussis.

Enhanced surveillance includes:

Laboratory confirmed case counts
Age distribution of cases
Geographic distribution across England
Temporal trends and seasonal patterns
Vaccination status of cases
Severity and outcomes (hospitalizations, deaths)

Clinical significance: Pertussis is particularly dangerous for:

Infants: Highest risk of severe disease and death
Unvaccinated children: Increased susceptibility
Adolescents and adults: Often milder but can transmit to vulnerable infants

Key surveillance findings typically include:

Cyclical patterns (3-5 year peaks)
Impact of maternal vaccination program
Vaccine effectiveness estimates
Outbreak detection and response

Public health importance: The surveillance data informs:

Vaccination program effectiveness evaluation
Need for booster doses
Maternal vaccination program impact
Early outbreak detection
Public health messaging and interventions

Despite high vaccination coverage, pertussis remains a public health challenge due to waning immunity and continued circulation. Enhanced surveillance is essential for monitoring trends and guiding control strategies.

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